URIEXO provides you with a one-two punch against bacteria…SHIELDING you from recurring UTIs.

URIEXO is different from other products available without prescription, in six important ways:

Unlike many of the other products available without a prescription, URIEXO has been thoroughly assessed for quality, safety and efficacy by Health Canada and has been assigned a Natural Product Number (NPN).  If a product in question DOES NOT have a Natural Product Number (NPN) printed on its label or box, it’s likely just a supplement and has not been thoroughly assessed for quality, safety and efficacy by Health Canada. As such, Health Canada cannot provide such an assurance.

Natural health products (NHPs) in Canada are regulated differently than supplements.

The regulatory systems for NHPs are essentially product-specific, meaning that the National Health Products Directorate evaluates and approves the NHP if and only if its efficacy and safety can be proven.  The level of evidence required is also dependent on the claim (disease risk reduction claims require stronger evidence, including clinical studies).  In a nutshell, Natural Health Products are more tightly regulated than functional foods or supplements as they fall under more stringent NHP regulations.


When purchasing a non-prescription product, look for the NPN number on the box as an assurance that it has been thoroughly assessed for quality, safety and efficacy by Health Canada.

Unlike many of the other products available without a prescription, URIEXO has been specially formulated with not one but TWO clinically active ingredients (D-Mannose and Proanthocyanidins), providing you with a two-pronged and scientifically proven defence, against recurring UTIs.   These two active ingredients bind with UTI-causing bacteria in your urinary tract in two separate ways, to maximize your protection against recurrent UTIs by preventing bacteria from sticking to your bladder wall and urinary tract, so that you can safely flush bacteria out of your system.  All the other products available on the market have only one of the active ingredients and many of these are at sub-therapeutic doses that do not confer a clinical benefit.

URIEXO combines D-Mannose and Proanthocyanidins (PACs), two clinically proven UTI-fighting ingredients to shield your body from harmful bacteria and naturally flush them away before an infection can start.

URIEXO combines D-Mannose and Proanthocyanidins (PACs), sourced from cranberry, at their clinically therapeutic doses, for maximum defense against UTIs. While some other non-prescription products may contain similar ingredients, the quantity of the ingredients is frequently at a sub-therapeutic dose and may not be clinically effective at this dose. URIEXO contains a clinically effective dose of both active ingredients that has been clinically proven to help prevent UTI recurrences and more importantly, assessed by Health Canada to be a clinically effective dose.

URIEXO combines D-Mannose and Proanthocyanidins (PACs), at clinically effective doses to provide you with a one-two punch against UTI-causing bacteria.

Our scientists and physicians carefully crafted URIEXO based on what’s been proven to work, and not old wives’ tales.   We leveraged the best clinical research available to create the URIEXO special formula. The research demonstrates how each ingredient is important in reaching bacteria in the urinary tract to help flush them out, keeping you healthy and off antibiotics.  Many of these studies have shown that you can reduce the risk of UTIs by 75% or more.

URIEXO shields the body from harmful bacteria and naturally flushes it out before UTIs can start.

URIEXO, a Natural Health Product to help prevent Urinary Tract Infections and its symptoms, has been reviewed and approved to be part of the new “Brand Recognition Program” recently introduced by the Society of Obstetricians and Gynaecologists of Canada (SOGC).

The SOGC Brand Recognition Program aims to assist Canadian consumers to make informed choices when selecting over-the-counter products. This program is designed for non-prescription/over-the-counter products that are found to safely and effectively promote female sexual and reproductive health.

Eligible products are required to have:

  • Received Health Canada licence for sale in the Canadian market;
  • Demonstrated reasonable evidence of safety and efficacy, and pose no undue harm;
  • Substantiated packaging claims and a perceived low risk.

Products are independently and carefully reviewed by a panel of medical professionals.

In a clinical study comparing 2-grams of D-Mannose vs. antibiotics, URIEXO significantly reduce the risk of contracting a recurrent UTI. Furthermore, URIEXO performed as well as antibiotics, but without the long-term risks of antibiotic resistance, and with a significantly lower risk of short-term side effects (RR 0.276, P < 0.0001).

URIEXO shields the body from harmful bacteria and naturally flushes it out before UTIs can start.

Optimized Preventative Protection at an affordable price!

We employ the DMAC, the most precise standard of measurement, to guarantee each daily dose contains the essential 36 mg of PACs, ensuring accuracy in the most meticulous manner. Additionally, we include 2000 mg of D-mannose in every daily dose for added protection. Why pay twice the price for a competing brand to achieve the same desired effect?

Can You take cranberry and D-mannose together?

Yes, you certainly can take cranberry and D-mannose at the same time! One 2020 study¹ concluded that administering D-mannose with cranberry extract showed ‘an increase in effectiveness when used in combination with empirical treatment for uncomplicated UTIs.’ So, not only is it safe to take both together, but the overall treatment looks to be more effective.

Another randomized study on peri- and postmenopausal women with recurrent UTIs showed that oral supplementation of a product containing cranberry and D-mannose, was well-tolerated and effective in UTI treatment and in reducing risk for recurrent UTIs.²

Keep in mind however, the first and only course of action for treating a UTI are antibiotics, however, treatments such as URIEXO which contain both D-mannose and PACs at their clinically effective dose can prevent UTIs by preventing bacteria from attaching in the first place.

  1. Rădulescu, Daniela et al. Combination of cranberry extract and D-mannose – possible enhancer of uropathogen sensitivity to antibiotics in acute therapy of urinary tract infections: Results of a pilot study. 2020. 
  2. De Leo V, Cappelli V, Massaro MG, Tosti C, Morgante G. Evaluation of the effects of a natural dietary supplement with cranberry, Noxamicina(R) and D-mannose in recurrent urinary infections in perimenopausal women. Minerva Ginecol. 2017;69(4):336–41.


  • Helps prevent Urinary Tract Infections and its symptoms:
    • Painful or difficult urination
    • Frequent urination
    • Urgency to urinate
    • Suprapubic/pelvic pain
  • Two Medicinal Ingredients:
    • D-Mannose (2000 mg/day)
    • PACs, sourced from cranberry (36mg/day)
  • Antibiotic-Free
  • Easy to Swallow Capsules

Break the Vicious Cycle of Recurrent UTIs with Double-Action URIEXO

Developing a daily routine with URIEXO is the secret to preventing and eliminating UTIs, once and for all.

Uriexo Vegicaps – For Urinary Tract Infection (UTI), Antibiotic-Free, D-Mannose & Proanthocyanidins (PACs)

Mode of Action: Click here to learn more about URIEXO’s two-pronged defence to shield you from bacteria without using antibiotics!

Treatment & Prevention: Click here to learn more about how to start your routine with URIEXO to prevent your next Urinary Tract Infection.

URIEXO vs. Antibiotics: Click here to learn more about how taking URIEXO can help you avoid taking antibiotics and more importantly, avoid antibiotic resistance.

Newsletters: Click here to access our newsletters on the latest news, tips, and updates relating to urinary health. 

FAQs: Click here to find the answers to commonly asked questions on Uriexo and urinary tract infections.

Our Products: Click here to to view Tyros Biopharma’s product lines. We are committed to providing high-quality products that empower women to lead healthy and fulfilling lives.