Up until now, the two most commonly used strategies to treat recurrent UTIs were long-term, low-dose antibiotic prophylaxis and post-coital antibiotic prophylaxis for women who have UTIs associated with sexual intercourse.

The reality is that antibiotics have their own set of complications. It is not uncommon for patients, particularly elderly patients, to develop severe allergic reactions or antibiotic-related diarrhea, both of which can be fatal in older adults.  Furthermore, over-dependence on antibiotic strategies can lead to bacterial resistance.

Break the Vicious Cycle of Recurrent UTIs with Double-Action URIEXO… An ounce of prevention is worth a pound of cure.

New non-prescription URIEXO is a clinically proven, non-antibiotic option to UTI prevention. Only URIEXO Double-Action is specially formulated with two clinically proven active ingredients (2000 mg of D-Mannose and 36 mg of PACs in its daily recommended dose) that have been demonstrated to be effective as prophylactic therapy for patients with recurrent urinary tract infections (UTIs).

URIEXO provides your patients with a two-pronged and scientifically proven defence, against recurring UTIs. These two active ingredients, bind with UTI-causing bacteria in the urinary tract in two separate ways, preventing bacteria from adhering to the bladder wall and urinary tract, so that bacteria can safely be flushed out with urination. This double mode of action helps prevent the pain associated with urinary tract infections, and more importantly, protects your patient’s kidneys from potential damage of recurring UTIs.

We take a UNIQUE approach to UTI prevention.

URIEXO SHIELDS your patients from recurring UTIs.

Optimized Preventative Protection at an affordable price!

We employ the DMAC/c-PAC, the most precise standard of measurement, to guarantee each daily dose contains the essential 36 mg of PACs, ensuring accuracy in the most meticulous manner. Additionally, we include 2000 mg of D-mannose in every daily dose for added protection. Why pay twice the price for a competing brand to achieve the same desired effect?

Click here to learn more about the different types of cranberry measurements and how URIEXO ensures you are optimally covered.

IMPORTANT NOTE: Be cautious of assertions from certain proanthocyanidin supplement manufacturers who claim superiority in their measurement methods without referencing accessible published literature. These are the same companies that may inaccurately state higher PAC content than what is indicated on their Health Canada license and packaging.
It’s crucial to remember that products subjected to comprehensive evaluation for quality, safety, and efficacy by Health Canada typically bear a Natural Product Number (NPN). Conversely, products lacking an NPN on their label or packaging likely haven’t undergone thorough Health Canada evaluation and may not meet stringent standards. Essentially, the Health Canada NPN guarantees that you receive precisely what is stated on the label and what you’ve paid for.

Can You take cranberry and D-mannose together?

Yes, you certainly can take cranberry and D-mannose at the same time! One 2020 study¹ concluded that administering D-mannose with cranberry extract showed ‘an increase in effectiveness when used in combination with empirical treatment for uncomplicated UTIs.’ So, not only is it safe to take both together, but the overall treatment looks to be more effective.

Another randomized study on peri- and postmenopausal women with recurrent UTIs showed that oral supplementation of a product containing cranberry and D-mannose, was well-tolerated and effective in UTI treatment and in reducing risk for recurrent UTIs.²

Keep in mind however, the first and only course of action for treating a UTI are antibiotics, however, treatments such as URIEXO which contain both D-mannose and PACs at their clinically effective dose can prevent UTIs by preventing bacteria from attaching in the first place.

  1. Rădulescu, Daniela et al. Combination of cranberry extract and D-mannose – possible enhancer of uropathogen sensitivity to antibiotics in acute therapy of urinary tract infections: Results of a pilot study. 2020. 
  2. De Leo V, Cappelli V, Massaro MG, Tosti C, Morgante G. Evaluation of the effects of a natural dietary supplement with cranberry, Noxamicina(R) and D-mannose in recurrent urinary infections in perimenopausal women. Minerva Ginecol. 2017;69(4):336–41.


  • Helps prevent Urinary Tract Infections and its symptoms:
    • Painful or difficult urination
    • Frequent urination
    • Urgency to urinate
    • Suprapubic/pelvic pain
  • Two Medicinal Ingredients:
    • D-Mannose (2000 mg/day)
    • PACs, sourced from cranberry (36mg/day)
  • Antibiotic-Free
  • Easy to Swallow Capsules

Uriexo is a product recognized by the Society of Obstetricians and Gynaecologists of Canada through the SOGC Brand Recognition Program.

Developing a daily routine with URIEXO is the secret to preventing and eliminating UTIs, once and for all.

Uriexo Vegicaps – For Urinary Tract Infection (UTI), Antibiotic-Free, D-Mannose & Proanthocyanidins (PACs)

Mechanism of Action: Click here to learn more about URIEXO’s unique mechanism of action in detail.

Clinical Studies: Click here to learn more about the clinical studies supporting URIEXO’s efficacy.

Downloads & Samples: Click here to download information or request samples of URIEXO for your patients.

PACs Measurement: Click here to learn more about the different types of cranberry measurements and how URIEXO ensures you are optimally covered.

FAQs: Click here to find the answers to commonly asked questions on Uriexo and urinary tract infections.

Our Products: Click here to to view Tyros Biopharma’s product lines. We are committed to providing high-quality products that empower women to lead healthy and fulfilling lives.